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L-Lysine is an essential amino acid that is not synthesized in adequate amounts by the body, so it must be obtained from dietary sources.

L-Lysine is particularly important for proper growth. L-Lysine also regulates calcium absorption and plays an important role in the formation of collagen.

L-Lysine aids in the production of antibodies, hormones, and enzymes, and helps to build muscle. It is beneficial for those recovering from surgery and sports injuries. It also lowers high serum triglyceride levels.

A vegetarian diet may not provide sufficient L-Lysine. In many areas of the world where diets are grain-based, this becomes important as a lysine deficiency can create a negative nitrogen balance and lead to kidney stones.

L-Lysine has the capacity for fighting cold sores and herpesviruses. Taking supplemental L-lysine, together with vitamin C with bioflavonoids, can effectively fight and/or prevent herpes outbreaks, especially if foods containing the amino acid arginine are avoided.

Supplementation of L-lysine also may decrease acute alcohol intoxication.

Some studies have found that lysine is beneficial in treating cardiovascular disease, osteoporosis, asthma, migraines, nasal polyps, and postepisiotomy pain.